Do | $$$$$
Hip boutique hotel in River North with a 10,000-sq.-ft. museum space dedicated to 21st century art.
After originating in Louisville in 2006, the 21c Museum Hotel has cemented itself as one of the most interesting boutique hotels in the nation. Its first Chicago location is a 297-room outlet in River North with a 10,000-sq.-ft. museum space exhibiting art of the 21st century.